Weight loss camps for young adults uk
Worldwide, an estimated 65 000 children under 15 years old develop the disease each year, and the global incidence in children continues to increase at a rate of 3% a year.1 2 The current incidence in the UK is around 26/100 000 per year.3Between 10% and 70% of these diagnosed children present in diabetic ketoacidosis, a metabolic derangement characterised by the triad of hyperglycaemia, acidosis, and ketonuria.
One author (JAUS) excluded 1333 of these as clearly irrelevant on the basis of title and abstract.
Protective factors were having a first degree relative with type 1 diabetes at the time of diagnosis (odds ratio 0.33 (0.08 to 1.26)), higher parental education (odds ratios 0.4 (0.20 to 0.79) and 0.64 (0.43 to 0.94) in two studies), and higher background incidence of type 1 diabetes (correlation coefficient –0.715).
The mean duration of symptoms was similar between children presenting with or without diabetic ketoacidosis (16.5 days (standard error 6.2) and 17.1 days (6.0) respectively), and up to 38.8% (285/735) of children who presented with diabetic ketoacidosis had been seen at least once by a doctor before diagnosis.
Conclusions Multiple factors affect the risk of developing diabetic ketoacidosis at the onset of type 1 diabetes in children and young adults, and there is potential time, scope, and opportunity to intervene between symptom onset and development of diabetic ketoacidosis for both parents and clinicians.
Type 1 diabetes is one of the most common endocrine diseases in children.